CD28 anticorps

N° du produit ABIN6941130

Cet anticorps anti-CD28 est un anticorps Souris Monoclonal détectant CD28 dans FACS, IF et Func. Adapté pour Humain.

Aperçu rapide pour CD28 anticorps (ABIN6941130)

Antigène: CD28

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: CB28

Détail du produit anti-CD28 anticorps

Specificité: Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Purification: Purified by Protein A/G

Immunogène: Recombinant human CD28 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Jurkat cells. Human lymph nodes and tonsils.

Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Functional Studies (Order Ab without BSA & Azide), ,Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Poids moléculaire: 44kDa (monomer), 88kDa (dimer)

ID gène: 940

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response