Recombinant BAX anticorps (AA 20-150)
Aperçu rapide pour Recombinant BAX anticorps (AA 20-150) (ABIN6942235)
Antigène
Voir toutes BAX AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-150
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Fonction
- Bax Recombinant Antibody
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- Recombinant human Bak between 20 to 150 amino acids
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:200-400), IF(1:50-200), Flow-Cyt(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Autre désignation
- Bax
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Sujet
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Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BCL2L4
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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ID gène
- 581
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UniProt
- Q07812
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Pathways
- Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Antigène
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