CD11b anticorps

N° du produit ABIN6942386

Cet anticorps anti-CD11b Monoclonal Lapin (Clone 9B3) (ABIN6942386) détecte spécifiquement CD11b dans WB, IHC (fro), IHC (p) et IF (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD11b anticorps (ABIN6942386)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 9B3

Détail du produit anti-CD11b anticorps

Fonction: CD11b Monoclonal Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant Human ITGAM

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:1000-2000)), IHC-P(IHC-P(1:200-800)), IHC-F(IHC-F(1:200-800)), IF(IHC-P)(IF(IHC-P)(1:200-800))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: CD11b

Sujet:

Synonyms: Antigen CD11b (p170), CD11 antigen like family member B, CD11 antigen like family member C, Cell surface glycoprotein MAC 1 subunit alpha, CR 3 alpha chain, CR3A, Integrin alpha M, Integrin alpha X, Integrin, alpha M (complement component 3 receptor 3 subunit), Integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Integrin, alpha X (complement component 3 receptor 4 subunit), ITGAM, ITGAX, Leu M5, alpha subunit, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor MO1, Leukocyte adhesion receptor p150,95, Leukocyte surface antigen p150,95, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MO1A, Myeloid membrane antigen, alpha subunit, Neutrophil adherence receptor alpha M subunit, p150 95 integrin alpha chain, SLEB6, ITAM_HUMAN, c equivalent, Integrin αM.

Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

ID gène: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation