DEPTOR anticorps (AA 151-250) (Biotin)

N° du produit ABIN6942875

Détail du produit anti-DEPTOR anticorps (Biotin)

Antigène: DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))

Épitope: AA 151-250

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEPTOR est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DEPTOR

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DEPTOR

Antigène: DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))

Autre désignation: DEPTOR (DEPTOR Produits)

Synonymes: anticorps DEP.6, anticorps DEPDC6, anticorps 4731402B04Rik, anticorps 9130412E02Rik, anticorps D15Ertd336e, anticorps D15Ertd597e, anticorps Depdc6, anticorps Depdc6-001, anticorps Depdc6-002, anticorps R75183, anticorps mKIAA4200, anticorps RGD1561030, anticorps RAPGEF4, anticorps DEP domain containing MTOR interacting protein, anticorps DEP domain containing MTOR-interacting protein, anticorps DEPTOR, anticorps Deptor

Sujet:

Synonyms: DEP domain containing 6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPDC6, DEPTOR, DPTOR_HUMAN.

Background: DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

ID gène: 64798

UniProt: Q8TB45

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Regulation of Cell Size, BCR Signaling, L'effet Warburg