SCARB1 anticorps

N° du produit ABIN6944824

L’anticorps anti-SCARB1 Monoclonal Lapin est utilisé pour la détection de SCARB1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, FACS, IHC (p), IF (cc) et IF (p).

Aperçu rapide pour SCARB1 anticorps (ABIN6944824)

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SCARB1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 1C2

Détail du produit anti-SCARB1 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant Scavenging Receptor SR-BI

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SCARB1

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: SCARB1

Sujet:

Synonyms: Scavenger receptor class B member 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SRB1, CLA-1, Scavenging Receptor SR-BI

Background: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.

ID gène: 949

UniProt: Q8WTV0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome