EIF2C3 anticorps (AA 1-175)

N° du produit ABIN6971365

Cet anticorps anti-EIF2C3 est un anticorps Souris Monoclonal détectant EIF2C3 dans ICC, IF, IP et ChIP. Adapté pour Humain.

Aperçu rapide pour EIF2C3 anticorps (AA 1-175) (ABIN6971365)

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2C3 est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Clone: 4B1-F6

Détail du produit anti-EIF2C3 anticorps

Épitope: AA 1-175

Attributs du produit: Argonaute 3 (Ago3, aka EIF2C3) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Ago3, however, lacks RNase activity and does not appear to cleave target mRNA molecules. Ago3 has both a PAZ and a PIWI domain, indicative of the Argonaute family of proteins. Ago3 antibody (mAb) (Clone 4B1-F6) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, Immunocytochemistry, Immunofluorescence and Immunoprecipitation, it has been shown to react with Human samples.

Purification: Protein G Chromatography

Immunogène: This Ago3 (Argonaute 3) antibody was raised against a recombinant protein corresponding to amino acids 1-175 of human Ago3.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur EIF2C3

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Autre désignation: Ago3

Poids moléculaire: 110 kDa

NCBI Accession: NP_079128

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway