SMARCAL1 anticorps

N° du produit ABIN6972741

Détail du produit anti-SMARCAL1 anticorps

Antigène: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMARCAL1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: SMARCAL1 / HARP (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, DNA-dependent ATPase A) is a member of the SWI / SNF family of ATPases and chromatin remodeling proteins. Unlike other SWI / SNF family members, SMARCAL1 / HARP has not been shown to remodel chromatin, but possesses an ATP-dependent annealing helicase activity. SMARCAL1 reanneals single-stranded DNA bubbles in DNA at DNA replication forks that are bound by Replication Protein A (RPA). Defects in SMARCAL1 / HARP are a cause of Schimke immuno-osseous dysplasia (SIOD) SIOD causes spondyloepiphyseal dysplasia (a disorder of bone growth that results in short stature, skeletal abnormalities, and problems with vision and hearing), renal dysfunction and T-cell immunodeficiency. SMARCAL1 / HARP antibody (mAb) (Clone 4B10) was raised in a Mouse host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Bovine, Human and Mouse samples.

Purification: Protein G Chromatography

Immunogène: This SMARCAL1 / HARP antibody was raised against purifed bovine SMARCAL1 / HARP protein.

Clone: 4B10

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur SMARCAL1

Antigène: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Autre désignation: SMARCAL1 / HARP (SMARCAL1 Produits)

Synonymes: anticorps SMARCAL1, anticorps im:7145331, anticorps si:ch211-239d11.1, anticorps harp, anticorps hharp, anticorps 6030401P21Rik, anticorps AI851716, anticorps Mharp, anticorps HARP, anticorps HHARP, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog, anticorps SMARCAL1, anticorps smarcal1, anticorps Smarcal1, anticorps smarcal1.L

Poids moléculaire: 150 kDa

NCBI Accession: NP_788839

Pathways: Embryonic Body Morphogenesis