EDC4 anticorps (AA 1-100) (Alexa Fluor 350)

N° du produit ABIN6976445

Détail du produit anti-EDC4 anticorps (Alexa Fluor 350)

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Épitope: AA 1-100

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDC4 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EDC4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EDC4

Antigène: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Autre désignation: EDC4 (EDC4 Produits)

Synonymes: anticorps VARICOSE, anticorps ge-1, anticorps hedls, anticorps rcd-8, anticorps GE1, anticorps Ge-1, anticorps HEDL5, anticorps HEDLS, anticorps RCD-8, anticorps RCD8, anticorps BC022641, anticorps si:ch211-237c7.1, anticorps wu:fe26b05, anticorps LRRG00115, anticorps Nrn1l, anticorps RGD1309136, anticorps enhancer of mRNA decapping 4, anticorps Transducin/WD40 repeat-like superfamily protein, anticorps enhancer of mRNA decapping 4 L homeolog, anticorps EDC4, anticorps VCS, anticorps edc4, anticorps Edc4, anticorps edc4.L

Sujet:

Synonyms: autoantigen, Autoantigen Ge 1, Autoantigen Ge-1, Autoantigen Ge1, Autoantigen RCD 8, Autoantigen RCD-8, Autoantigen RCD8, edc4, EDC4_HUMAN, Enhancer of mRNA decapping 4, Enhancer of mRNA-decapping protein 4, Ge 1, Hedls, Human enhancer of decapping large subunit, RCD 8.

Background: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.

ID gène: 23644

UniProt: Q6P2E9