MAP2K7 anticorps (pThr275) (AbBy Fluor® 647)

N° du produit ABIN6980156

L’anticorps Lapin Polyclonal anti-MAP2K7 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter MAP2K7 dans des échantillons de Rat.

Aperçu rapide pour MAP2K7 anticorps (pThr275) (AbBy Fluor® 647) (ABIN6980156)

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MAP2K7 anticorps (AbBy Fluor® 647)

Épitope: pThr275

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human MEK7 around the phosphorylation site of Thr275

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MEK7

Sujet:

Synonyms: MEK7 (phospho T275), MEK7 (phospho S275), p-MEK7 (phospho S275), c-Jun N-terminal kinase kinase 2, Dual specificity mitogen activated protein kinase kinase 7, Dual specificity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNK-activating kinase 2, Jnkk 2, Jnkk-2, Jnkk2, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MAPKK-7, MAPKK7, MEK 7, Mitogen Activated Protein Kinase kinase 7, MKK 7, MKK-7, MKK7, MP2K7_HUMAN, PRKMK 7, PRKMK-7, PRKMK7, Sek 2, Sek-2, Sek2.

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].

ID gène: 5609

UniProt: O14733

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling