TOPORS anticorps (AA 21-120) (FITC)

N° du produit ABIN6987239

Détail du produit anti-TOPORS anticorps (FITC)

Antigène: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOPORS est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human p53 BP3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TOPORS

Antigène: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Autre désignation: p53 BP3 (TOPORS Produits)

Synonymes: anticorps CG15104, anticorps Dmel\\CG15104, anticorps TOPORS, anticorps dTopors, anticorps dtopors, anticorps fi75f04, anticorps wu:fi75f04, anticorps AW105885, anticorps LUN, anticorps TP53BPL, anticorps p53BP3/LUN, anticorps P53BP3, anticorps RP31, anticorps Topoisomerase I-interacting protein, anticorps TOP1 binding arginine/serine rich protein, anticorps topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, anticorps topoisomerase I binding, arginine/serine-rich b, anticorps topoisomerase I binding, arginine/serine-rich, anticorps Topors, anticorps TOPORS, anticorps topors, anticorps toporsb

Sujet:

Synonyms: AW105885, E3 ubiquitin protein ligase Topors, E3 ubiquitin-protein ligase Topors, LUN, p53 binding protein 3, p53 BP3/LUN, p53-binding protein 3, p53BP3, p53BP3/LUN, Retinitis pigmentosa 31, RP31, SUMO1 protein E3 ligase Topors, SUMO1-protein E3 ligase Topors, Topoisomerase I binding arginine/serine rich, Topoisomerase I binding arginine/serine rich protein, Topoisomerase I binding protein, Topoisomerase I binding RING finger protein, Topoisomerase I-binding arginine/serine-rich protein, Topoisomerase I-binding RING finger protein, Topoisomerase I-binding RS protein, TOPORS, TOPRS_HUMAN, TP53BPL, Tumor protein p53 binding protein, Tumor suppressor p53 binding protein 3, Tumor suppressor p53-binding protein 3.

Background: Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.

ID gène: 10210

UniProt: Q9NS56

Pathways: Maintenance of Protein Location