SOCS6 anticorps (AA 21-120)
Aperçu rapide pour SOCS6 anticorps (AA 21-120) (ABIN6989474)
Antigène
Voir toutes SOCS6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-120
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Réactivité croisée
- Poulet, Souris
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Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SOCS6
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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Autre désignation
- SOCS6
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Sujet
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Synonyms: CIS-4, CIS4, Cish4, Cytokine inducible SH2 protein 4, Cytokine-inducible SH2 protein 4, HSPC060, SOCS-4, SOCS-6, SOCS4, Socs6, SOCS6_HUMAN, SSI4, STAI4, STAT induced STAT inhibitor 4, STAT4, STATI4, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 6.
Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008].
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ID gène
- 9306
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UniProt
- O14544
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Pathways
- Signalistation JAK/STAT, Carbohydrate Homeostasis
Antigène
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