WAPAL anticorps

N° du produit ABIN6989652

Détail du produit anti-WAPAL anticorps

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp WAPAL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within N-terminal human WAPL

Clone: 7C15

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur WAPAL

Antigène: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Autre désignation: WAPL (WAPAL Produits)

Synonymes: anticorps RGD1308960, anticorps FOE, anticorps KIAA0261, anticorps WAPL, anticorps 2410073G16, anticorps A530089A20Rik, anticorps BC037674, anticorps mKIAA0261, anticorps mWAPL, anticorps WAPL cohesin release factor, anticorps Wapl, anticorps WAPL, anticorps wapl

Sujet:

Synonyms: FOE antibody, Friend of EBNA2 (Epstein Barr virus nuclear protein 2) antibody, Friend of EBNA2 protein antibody, KIAA0261 antibody, OTTHUMP00000020004 antibody, WAPAL antibody, WAPL antibody, WAPL_HUMAN antibody, Wings apart like homolog antibody, Wings apart like homolog (Drosophila) antibody, Wings apart-like protein homolog antibody

Background: Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Tissue specificity: Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.

ID gène: 23063

UniProt: Q7Z5K2

Pathways: Chromatin Binding