STAT5A anticorps (pTyr694)
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- Antigène Voir toutes STAT5A Anticorps
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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Épitope
- pTyr694
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp STAT5A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein
- Clone
- 3H8
- Isotype
- IgG
- Top Product
- Discover our top product STAT5A Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
- Autre désignation
- Stat5 (STAT5A Produits)
- Synonymes
- anticorps MGF, anticorps STAT5, anticorps AA959963, anticorps Stat5, anticorps STAT5A/MGF, anticorps STATA5, anticorps STAT5A, anticorps stat5, anticorps stat5b, anticorps signal transducer and activator of transcription 5A, anticorps signal transducer and activator of transcription 5a, anticorps STAT5A, anticorps Stat5a, anticorps stat5a, anticorps LOC100348518, anticorps LOC100716811
- Sujet
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Synonyms: MGF antibody, Signal transducer and activator of transcription 5A antibody, Signal Transducer and Activator of Transcription 5B antibody, STA5A_HUMAN antibody, STAT 5A antibody, STAT 5B antibody, STAT5 antibody, STAT5A antibody, STAT5B antibody, Transcription factor STAT5A antibody, Transcription factor STAT5B antibody
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- ID gène
- 6776
- UniProt
- P42229
- Pathways
- Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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