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IRAK1 anticorps (AA 618-712)
IRAK1
Reactivité: Humain, Souris
WB, ELISA, IHC (p)
Hôte: Souris
Monoclonal
8F1A7
unconjugated
N° du produit ABIN6990202
Détail du produit anti-IRAK1 anticorps
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Antigène
Voir toutes IRAK1 Anticorps
IRAK1
(Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
Épitope
Tous les épitopes à travers IRAK1 Anticorps.
AA 618-712
Reactivité
Toutes les réactivités sur IRAK1 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur IRAK1 Anticorps
Souris
Clonalité
Toutes les clonalités sur IRAK1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers IRAK1 Anticorps
Cet anticorp IRAK1 est non-conjugé
Application
Tous les applications à travers IRAK1 Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
IRAK Monoclonal Antibody is Protein G purified.
Immunogène
Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
Clone
8F1A7
Isotype
IgG1
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Information d'application
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Indications d'application
IRAK antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
IRAK Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
IRAK monoclonal antibody can be stored at -20°C, stable for one year.
Détails sur IRAK1
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Antigène
IRAK1
(Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
Autre désignation
IRAK (IRAK1 Produits )
Synonymes
anticorps IRAK1, anticorps IRAK, anticorps pelle, anticorps AA408924, anticorps IRAK-1, anticorps IRAK1-S, anticorps Il1rak, anticorps Plpk, anticorps mPLK, anticorps RGD1563841, anticorps interleukin 1 receptor associated kinase 1, anticorps interleukin-1 receptor-associated kinase 1, anticorps IRAK1, anticorps irak1, anticorps Irak1
Sujet
IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κ,B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
ID gène
3654
UniProt
P51617
Pathways
Signalisation NF-kappaB , Signalisation TLR , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Toll-Like Receptors Cascades
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