CASP14 anticorps (C-Term)

N° du produit ABIN6990387

Cet anticorps anti-CASP14 est un anticorps Lapin Polyclonal détectant CASP14 dans WB, ELISA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CASP14 anticorps (C-Term) (ABIN6990387)

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CASP14 anticorps

Épitope: C-Term

Purification: Caspase-14 Antibody is affinity chromatography purified via peptide column.

Immunogène: Caspase-14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14. The immunogen is located within the last 50 amino acids of Caspase-14.

Isotype: IgG

Information d'application

Indications d'application: Caspase-14 antibody can be used for the detection of caspase-14 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Caspase-14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Caspase-14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CASP14

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Autre désignation: Caspase-14

Sujet: Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Poids moléculaire: Predicted: 28 kDa

Observed: 27 kDa

ID gène: 23581

UniProt: P31944