TLR8 anticorps (N-Term)

N° du produit ABIN6990452

L’anticorps Lapin Polyclonal anti-TLR8 a été validé pour ELISA et IHC (p). Il convient pour détecter TLR8 dans des échantillons de Humain et Souris.

Aperçu rapide pour TLR8 anticorps (N-Term) (ABIN6990452)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TLR8 anticorps

Épitope: N-Term

Specificité: At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members

Purification: TLR8 Antibody is affinity chromatography purified via peptide column.

Immunogène: TLR8 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TLR8. The immunogen is located within the first 50 amino acids of TLR8.

Isotype: IgG

Information d'application

Indications d'application: TLR8 antibody can be used for detection of TLR8 by immunohistochemistry at 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8

Sujet: TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

ID gène: 51311

NCBI Accession: NP_619542

UniProt: Q9NR97

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades