TLR8 anticorps (AA 790-840)

N° du produit ABIN6990456

Cet anticorps anti-TLR8 est un anticorps Lapin Polyclonal détectant TLR8 dans WB, ELISA, ICC et IF. Adapté pour Humain et Souris.

Aperçu rapide pour TLR8 anticorps (AA 790-840) (ABIN6990456)

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-TLR8 anticorps

Épitope: AA 790-840

Purification: TLR8 Antibody is affinity chromatography purified via peptide column.

Immunogène: TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8. The immunogen is located within amino acids 790 - 840 of TLR8.

Isotype: IgG

Information d'application

Indications d'application: TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TLR8

Antigène: TLR8 (Toll-Like Receptor 8 (TLR8))

Autre désignation: TLR8

Sujet: TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

Poids moléculaire: Predicted: 112 kDa

Observed: 107 kDa

ID gène: 51311

NCBI Accession: NP_619542

UniProt: Q9NR97

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades