PLEKHM3 anticorps (C-Term)

N° du produit ABIN6991226

Détail du produit anti-PLEKHM3 anticorps

Antigène: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLEKHM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: PLEKHM3 Antibody is affinity chromatography purified via peptide column.

Immunogène: PLEKHM3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM3. The immunogen is located within the last 50 amino acids of PLEKHM3.

Isotype: IgG

Information d'application

Indications d'application: PLEKHM3 antibody can be used for detection of PLEKHM3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PLEKHM3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PLEKHM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PLEKHM3

Antigène: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Autre désignation: PLEKHM3 (PLEKHM3 Produits)

Synonymes: anticorps PLEKHM1L, anticorps DAPR, anticorps 9430067K14Rik, anticorps A230102O09Rik, anticorps AI449570, anticorps Plekhm1l, anticorps Dapr, anticorps RGD1307151, anticorps pleckstrin homology domain containing, family M, member 3, anticorps pleckstrin homology domain containing M3, anticorps pleckstrin homology domain containing M3 L homeolog, anticorps PLEKHM3, anticorps Plekhm3, anticorps plekhm3.L

Sujet: PLEKHM3 Antibody: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.

ID gène: 389072

UniProt: Q6ZWE6