SLC39A5 anticorps (AA 330-380)

N° du produit ABIN6991454

Détail du produit anti-SLC39A5 anticorps

Antigène: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Épitope: AA 330-380

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: ZIP5 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZIP5 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIP5. The immunogen is located within amino acids 330 - 380 of ZIP5.

Isotype: IgG

Information d'application

Indications d'application: ZIP5 antibody can be used for detection of ZIP5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIP5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZIP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SLC39A5

Antigène: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Autre désignation: ZIP5 (SLC39A5 Produits)

Synonymes: anticorps 1810013D05Rik, anticorps 2010205A06Rik, anticorps Zip5, anticorps LZT-Hs7, anticorps ZIP5, anticorps solute carrier family 39 member 5, anticorps solute carrier family 39 (metal ion transporter), member 5, anticorps SLC39A5, anticorps Slc39a5

Sujet: ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

ID gène: 283375

NCBI Accession: NP_001128667

UniProt: Q6ZMH5

Pathways: Transition Metal Ion Homeostasis