SLC39A6 anticorps (AA 430-480)

N° du produit ABIN6991455

Détail du produit anti-SLC39A6 anticorps

Antigène: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Épitope: AA 430-480

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: ZIP6 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZIP6 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP6. The immunogen is located within amino acids 430 - 480 of ZIP6.

Isotype: IgG

Information d'application

Indications d'application: ZIP6 antibody can be used for detection of ZIP6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIP6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZIP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SLC39A6

Antigène: SLC39A6 (Solute Carrier Family 39 (Zinc Transporter), Member 6 (SLC39A6))

Autre désignation: ZIP6 (SLC39A6 Produits)

Synonymes: anticorps liv1, anticorps wu:fc25a09, anticorps ZIP6, anticorps Ermelin, anticorps LIV-1, anticorps solute carrier family 39 (zinc transporter), member 6, anticorps solute carrier family 39 member 6, anticorps solute carrier family 39 (metal ion transporter), member 6, anticorps slc39a6, anticorps SLC39A6, anticorps Slc39a6

Sujet: ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line, down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

ID gène: 25800

NCBI Accession: NP_001092876

UniProt: Q13433

Pathways: Transition Metal Ion Homeostasis