ZIP10 Antibody is affinity chromatography purified via peptide column.
Immunogène
ZIP10 antibody was raised against an 18 amino acid synthetic peptide near the center of human ZIP10. The immunogen is located within amino acids 550 - 600 of ZIP10.
SLC39A10
Reactivité: Humain, Souris, Rat
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
ZIP10 antibody can be used for detection of ZIP10 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
ZIP10 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
ZIP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
SLC39A10
(Solute Carrier Family 39 (Zinc Transporter), Member 10 (SLC39A10))
anticorps LZT-Hs2, anticorps 2900042E17Rik, anticorps 5430433I10, anticorps mKIAA1265, anticorps Slc39a10, anticorps Zip10, anticorps zgc:63552, anticorps DKFZp459C165, anticorps solute carrier family 39 member 10, anticorps solute carrier family 39 (zinc transporter), member 10, anticorps solute carrier family 39 (zinc transporter), member 4-like, anticorps SLC39A10, anticorps Slc39a10, anticorps Slc39a4l, anticorps slc39a10
Sujet
ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.