FOXRED2 anticorps (N-Term)

N° du produit ABIN6991660

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXRED2 dans ELISA, WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour FOXRED2 anticorps (N-Term) (ABIN6991660)

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXRED2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-FOXRED2 anticorps

Épitope: AA 70-120, N-Term

Purification: FOXRED2 Antibody is affinity chromatography purified via peptide column.

Immunogène: FOXRED2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FOXRED2. The immunogen is located within amino acids 70 - 120 of FOXRED2.

Isotype: IgG

Information d'application

Indications d'application: FOXRED2 antibody can be used for detection of FOXRED2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FOXRED2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FOXRED2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FOXRED2

Antigène: FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))

Autre désignation: FOXRED2

Sujet: FOXRED2 Antibody: FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.

ID gène: 80020

UniProt: Q8IWF2

Pathways: SARS-CoV-2 Protein Interactome