PTPRD anticorps (N-Term)

N° du produit ABIN6991696

Détail du produit anti-PTPRD anticorps

Antigène: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRD est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: PTPRD antibody is human specific. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. PTPRD cleavage products are often observed in vivo

Purification: PTPRD Antibody is affinity chromatography purified via peptide column.

Immunogène: PTPRD antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PTPRD. The immunogen is located within the first 50 amino acids of PTPRD.

Isotype: IgG

Information d'application

Indications d'application: PTPRD antibody can be used for detection of PTPRD by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PTPRD Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PTPRD antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PTPRD

Antigène: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Autre désignation: PTPRD (PTPRD Produits)

Synonymes: anticorps HPTP, anticorps HPTPD, anticorps HPTPDELTA, anticorps PTPD, anticorps RPTPDELTA, anticorps 1110002J03Rik, anticorps 3000002J10Rik, anticorps B230219D21Rik, anticorps R-PTP-delta, anticorps ptprd, anticorps zgc:165626, anticorps ptpdelta, anticorps rptpdelta, anticorps xptp-d, anticorps protein tyrosine phosphatase, receptor type D, anticorps protein tyrosine phosphatase, receptor type, D, anticorps receptor-type tyrosine-protein phosphatase delta, anticorps protein tyrosine phosphatase, receptor type, D, b, anticorps protein tyrosine phosphatase, receptor type D S homeolog, anticorps PTPRD, anticorps Ptprd, anticorps LOC100155429, anticorps ptprdb, anticorps ptprd.S

Sujet: PTPRD Antibody: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.

Poids moléculaire: Predicted: 165, 210 kDa (130 kDa for cleavage product)

Observed: 130 kDa

ID gène: 5789

NCBI Accession: NP_569075

UniProt: P23468

Pathways: Synaptic Membrane