LMX1A anticorps (C-Term)

N° du produit ABIN6991775

Détail du produit anti-LMX1A anticorps

Antigène: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Épitope: AA 300-350, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMX1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B.

Purification: LMX1A Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A. The immunogen is located within amino acids 300 - 350 of LMX1A.

Isotype: IgG

Information d'application

Indications d'application: LMX1A antibody can be used for detection of LMX1A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LMX1A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LMX1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LMX1A

Antigène: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Autre désignation: LMX1A (LMX1A Produits)

Synonymes: anticorps Lmx1.1, anticorps dr, anticorps dreher, anticorps sst, anticorps LMX1, anticorps LMX1.1, anticorps si:ch211-260g14.3, anticorps LIM homeobox transcription factor 1 alpha, anticorps LIM homeobox transcription factor 1, alpha, anticorps Lmx1a, anticorps LMX1A, anticorps lmx1a

Sujet: LMX1A Antibody: The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.

Poids moléculaire: 42 kDa

ID gène: 4009

NCBI Accession: NP_796372

UniProt: Q8TE12

Pathways: Dopaminergic Neurogenesis