TYK2 anticorps (N-Term)

N° du produit ABIN6991802

L’anticorps Lapin Polyclonal anti-TYK2 a été validé pour WB, ELISA et IF. Il convient pour détecter TYK2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TYK2 anticorps (N-Term) (ABIN6991802)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TYK2 anticorps

Épitope: AA 90-140, N-Term

Specificité: At least three isoforms of TYK2 are known to exist, this antibody only detects the two longest isoforms.

Purification: TYK2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2. The immunogen is located within amino acids 90 - 140 of TYK2.

Isotype: IgG

Information d'application

Indications d'application: TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TYK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TYK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2

Sujet: TYK2 Antibody: TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Poids moléculaire: Predicted: 131 kDa

ID gène: 7297

NCBI Accession: NP_003322

UniProt: P29597

Pathways: Signalistation JAK/STAT, Hepatitis C