Kallikrein 4 anticorps (AA 80-130)

N° du produit ABIN6991891

Cet anticorps Lapin Polyclonal détecte spécifiquement Kallikrein 4 dans WB, ELISA, IHC (p) et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Kallikrein 4 anticorps (AA 80-130) (ABIN6991891)

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Kallikrein 4 anticorps

Épitope: AA 80-130

Specificité: KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist.

Purification: KLK4 Antibody is affinity chromatography purified via peptide column.

Immunogène: KLK4 antibody was raised against a 15 amino acid peptide near the center of human KLK4. The immunogen is located within amino acids 80 - 130 of KLK4 .

Isotype: IgG

Information d'application

Indications d'application: KLK4 antibody can be used for detection of KLK4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLK4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KLK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Kallikrein 4

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Autre désignation: KLK4

Sujet: Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4).

Poids moléculaire: Predicted: 28 kDa

Observed: 31kDa

ID gène: 9622

NCBI Accession: NP_004908

UniProt: Q9Y5K2

Pathways: Système du Complément