RHOT1 anticorps (N-Term)

N° du produit ABIN6992082

Détail du produit anti-RHOT1 anticorps

Antigène: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Épitope: AA 40-90, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: RHOT1 antibody is human, mouse and rat reactive. At least three isoforms of RHOT1 are known to exist, this antibody will detect all three isoforms.

Purification: RHOT1 antibody is affinity chromatography purified via peptide column.

Immunogène: RHOT1 antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOT1. The immunogen is located within amino acids 40 - 90 of RHOT1.

Isotype: IgG

Information d'application

Indications d'application: RHOT1 antibody can be used for detection of RHOT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RHOT1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RHOT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur RHOT1

Antigène: RHOT1 (Ras Homolog Gene Family, Member T1 (RHOT1))

Autre désignation: RHOT1 (RHOT1 Produits)

Synonymes: anticorps rhot1, anticorps zgc:55581, anticorps zgc:77063, anticorps wu:fd14e11, anticorps wu:fi14a05, anticorps arht2, anticorps miro-2, anticorps rasl, anticorps ARHT1, anticorps MIRO-1, anticorps MIRO1, anticorps 2210403N23Rik, anticorps AA415293, anticorps AF244542, anticorps AI834919, anticorps Arht1, anticorps C430039G08Rik, anticorps Miro1, anticorps miro1, anticorps si:dkeyp-97g3.6, anticorps ras homolog family member T1a, anticorps ras homolog family member T2, anticorps ras homolog family member T1, anticorps ras homolog family member T1 L homeolog, anticorps rhot1a, anticorps rhot2, anticorps RHOT1, anticorps rhot1, anticorps rhot1.L, anticorps Rhot1, anticorps rhot1b

Sujet: The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria (1). RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria (2,3). Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility (4).

Poids moléculaire: Predicted: 76 kDa

Observed: 78 kDa

ID gène: 55288

NCBI Accession: NP_001028740

UniProt: Q8IXI2