SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist.
Purification
SLC1A7 antibody is affinity chromatography purified via peptide column.
Immunogène
SLC1A7 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLC1A7. The immunogen is located within amino acids 460 - 510 of SLC1A7.
SLC1A7 antibody can be used for detection of SLC1A7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
SLC1A7 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
SLC1A7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
SLC1A7
(Solute Carrier Family 1 (Glutamate Transporter), Member 7 (SLC1A7))
anticorps SLC1A7, anticorps si:ch211-284b7.1, anticorps slc1a7, anticorps A930031E15Rik, anticorps Eaat5, anticorps AAAT, anticorps EAAT5, anticorps solute carrier family 1 member 7, anticorps solute carrier family 1 (glutamate transporter), member 7a, anticorps solute carrier family 1 (glutamate transporter), member 7, anticorps SLC1A7, anticorps slc1a7a, anticorps Slc1a7
Sujet
The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).