PACS1 anticorps (AA 430-480)

N° du produit ABIN6992139

Détail du produit anti-PACS1 anticorps

Antigène: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Épitope: AA 430-480

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.

Purification: PACS1 antibody is affinity chromatography purified via peptide column.

Immunogène: PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.

Isotype: IgG

Information d'application

Indications d'application: PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PACS1

Antigène: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Autre désignation: PACS1 (PACS1 Produits)

Synonymes: anticorps MRD17, anticorps AI325977, anticorps Pacs-1, anticorps phosphofurin acidic cluster sorting protein 1, anticorps PACS1, anticorps Pacs1

Sujet: The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).

Poids moléculaire: Predicted: 106 kDa

Observed: 105 kDa

ID gène: 55690

NCBI Accession: NP_060496

UniProt: Q6VY07