STIL anticorps

N° du produit ABIN7233972

Détail du produit anti-STIL anticorps

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIL est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant Human SCL-interrupting locus protien

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur STIL

Antigène: STIL (SCL/TAL1 Interrupting Locus (STIL))

Autre désignation: STIL (STIL Produits)

Synonymes: anticorps Sil, anticorps MCPH7, anticorps SIL, anticorps chunp6907, anticorps sill, anticorps zgc:110502, anticorps STIL, centriolar assembly protein, anticorps Scl/Tal1 interrupting locus, anticorps STIL, centriolar assembly protein L homeolog, anticorps scl/tal1 interrupting locus, anticorps Stil, anticorps STIL, anticorps stil.L, anticorps stil

Sujet: This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q15468

Pathways: Tube Formation