Nebulin anticorps

N° du produit ABIN7238231

Détail du produit anti-Nebulin anticorps

Antigène: Nebulin (NEB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nebulin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human NEB

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Nebulin

Antigène: Nebulin (NEB)

Autre désignation: NEB (NEB Produits)

Synonymes: anticorps im:6904860, anticorps im:7001777, anticorps im:7144538, anticorps im:7150492, anticorps wu:fc33b04, anticorps si:ch211-168m7.5, anticorps NEB, anticorps NEB177D, anticorps NEM2, anticorps AI595938, anticorps nebulin, anticorps neb, anticorps NEB, anticorps Neb, anticorps LOC100516703

Classe de substances: Chemical

Sujet: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4 % of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.

NCBI Accession: NP_001157979

UniProt: P20929