SCN1A anticorps

N° du produit ABIN7238339

Détail du produit anti-SCN1A anticorps

Antigène: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN1A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SCN1A

Antigène: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Autre désignation: SCN1A (SCN1A Produits)

Synonymes: anticorps SCN9A, anticorps SCN1A, anticorps B230332M13, anticorps Nav1.1, anticorps EIEE6, anticorps FEB3, anticorps FEB3A, anticorps FHM3, anticorps GEFSP2, anticorps HBSCI, anticorps NAC1, anticorps SCN1, anticorps SMEI, anticorps sodium voltage-gated channel alpha subunit 1, anticorps sodium voltage-gated channel alpha subunit 9, anticorps sodium channel, voltage-gated, type I, alpha, anticorps SCN1A, anticorps SCN9A, anticorps Scn1a

Sujet: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops, each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

NCBI Accession: NP_001159435

UniProt: P35498