PLAT anticorps
Aperçu rapide pour PLAT anticorps (ABIN7238384)
Antigène
Voir toutes PLAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human PLAT
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Isotype
- IgG
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Indications d'application
- WB 1:200-1:1000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.4 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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Autre désignation
- PLAT
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Sujet
- This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
- 63 kDa
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NCBI Accession
- NP_000921
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UniProt
- P00750
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Pathways
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
Antigène
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