EID1 anticorps

N° du produit ABIN7241222

Détail du produit anti-EID1 anticorps

Antigène: EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EID1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human EID1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EID1

Antigène: EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))

Autre désignation: EID1 (EID1 Produits)

Synonymes: anticorps C15orf3, anticorps CRI1, anticorps EID-1, anticorps IRO45620, anticorps PTD014, anticorps RBP21, anticorps 2610002K20Rik, anticorps Cri1, anticorps ORF12, anticorps PNAS-22, anticorps RGD1562702, anticorps EP300 interacting inhibitor of differentiation 1, anticorps EID1, anticorps Eid1

Sujet: E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

NCBI Accession: NP_055150

UniProt: Q9Y6B2