SMAD4 anticorps

N° du produit ABIN7243955

Cet anticorps anti-SMAD4 est un anticorps Lapin Polyclonal détectant SMAD4 dans ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SMAD4 anticorps (ABIN7243955)

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SMAD4 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Fusion protein of human SMAD4

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-200, ELISA 1:1000-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMAD4

Antigène: SMAD4 (SMAD Family Member 4 (SMAD4))

Autre désignation: SMAD4

Sujet: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.

Poids moléculaire: 60 kDa

UniProt: Q13485

Pathways: Cycle Cellulaire, Chromatin Binding, Autophagy