VPS4A anticorps

N° du produit ABIN7244423

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS4A dans IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour VPS4A anticorps (ABIN7244423)

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4A est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-VPS4A anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human VPS4A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur VPS4A

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: VPS4A

Sujet: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18.

NCBI Accession: NP_037377

UniProt: Q9UN37

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events