VPS4A anticorps (N-Term)

N° du produit ABIN6243379

Détail du produit anti-VPS4A anticorps

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Épitope: AA 44-77, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS4A est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VPS4A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-77amino acids from the N-terminal region of human VPS4A.

Clone: RB49739

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur VPS4A

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: VPS4A (VPS4A Produits)

Synonymes: anticorps vsp4, anticorps SKD1, anticorps SKD1A, anticorps SKD2, anticorps VPS4, anticorps VPS4-1, anticorps zgc:153907, anticorps 4930589C15Rik, anticorps AI325971, anticorps AW553189, anticorps vacuolar protein sorting 4 homolog A, anticorps vacuolar sorting protein 4, anticorps vacuolar protein sorting 4 homolog A L homeolog, anticorps vacuolar protein sorting 4a homolog A (S. cerevisiae), anticorps vacuolar protein sorting 4A, anticorps VPS4A, anticorps TP03_0351, anticorps vps4a, anticorps vps4a.L, anticorps Vps4a

Sujet: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis.

Poids moléculaire: 48898

UniProt: Q9UN37

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events