Prokineticin Receptor 1 anticorps

N° du produit ABIN7245161

L’anticorps anti-Prokineticin Receptor 1 Polyclonal Lapin est utilisé pour la détection de Prokineticin Receptor 1 dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour Prokineticin Receptor 1 anticorps (ABIN7245161)

Antigène: Prokineticin Receptor 1 (PROKR1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prokineticin Receptor 1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Prokineticin Receptor 1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human PROKR1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Prokineticin Receptor 1

Antigène: Prokineticin Receptor 1 (PROKR1)

Autre désignation: PROKR1

Sujet: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage.PROKR1 (Prokineticin Receptor 1) is a Protein Coding gene. Diseases associated with PROKR1 include Ectopic Pregnancy. Among its related pathways are Peptide ligand-binding receptors and RET signaling. GO annotations related to this gene include G-protein coupled receptor activity and neuropeptide Y receptor activity. An important paralog of this gene is PROKR2.

UniProt: Q8TCW9

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma