Prokineticin Receptor 1 anticorps (AA 30-110)

N° du produit ABIN7216600

Cet anticorps Lapin Polyclonal détecte spécifiquement Prokineticin Receptor 1 dans ELISA, WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Prokineticin Receptor 1 anticorps (AA 30-110) (ABIN7216600)

Antigène: Prokineticin Receptor 1 (PROKR1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prokineticin Receptor 1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Prokineticin Receptor 1 anticorps

Épitope: AA 30-110

Fonction: Rabbit Anti-PKR1 Polyclonal Antibody

Specificité: PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human PKR1 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:100-500,ELISA 1:5000-20000,IHC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Prokineticin Receptor 1

Antigène: Prokineticin Receptor 1 (PROKR1)

Autre désignation: PKR1

Sujet: PROKR1, GPR73, PKR1, Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73aPROKR1 encodes a member of the G-protein-coupled receptor family. prokineticin receptor 1 binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. Prokineticin receptor 1 is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. Prokineticin receptor 1 may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in PROKR1 may be associated with recurrent miscarriage.

Poids moléculaire: 45kD

ID gène: 10887

UniProt: Q8TCW9

Pathways: Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma