CEMIP anticorps

N° du produit ABIN7245494

Détail du produit anti-CEMIP anticorps

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEMIP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CEMIP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CEMIP

Antigène: CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))

Autre désignation: CEMIP (CEMIP Produits)

Synonymes: anticorps CCSP1, anticorps TMEM2L, anticorps 3110012M15Rik, anticorps mKIAA1412, anticorps 12H19.01.T7, anticorps 6330404C01Rik, anticorps AY007814, anticorps Kiaa1199, anticorps KIAA1199, anticorps cell migration inducing hyaluronan binding protein, anticorps transmembrane protein 2, anticorps cell migration inducing protein, hyaluronan binding, anticorps CEMIP, anticorps Tmem2, anticorps TMEM2, anticorps Cemip

Sujet: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

UniProt: Q8WUJ3