WISP3 anticorps

N° du produit ABIN7003817

Cet anticorps Lapin Polyclonal détecte spécifiquement WISP3 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour WISP3 anticorps (ABIN7003817)

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-WISP3 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human WISP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur WISP3

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Autre désignation: WISP3

Sujet: WISP3 (WNT1 Inducible Signaling Pathway Protein 3) is a Protein Coding gene. Diseases associated with WISP3 include Arthropathy, Progressive Pseudorheumatoid, Of Childhood and Arthropathy. GO annotations related to this gene include growth factor activity and integrin binding. An important paralog of this gene is WISP1.This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 39 kDa

UniProt: O95389

Pathways: Signalisation WNT, Growth Factor Binding