Sialoadhesin/CD169 anticorps

N° du produit ABIN7249626

Détail du produit anti-Sialoadhesin/CD169 anticorps

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sialoadhesin/CD169 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse CD169

Isotype: IgG

Information d'application

Indications d'application: IHC 1:200-1:800

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Sialoadhesin/CD169

Antigène: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Autre désignation: CD169 (SIGLEC1 Produits)

Synonymes: anticorps Cd169, anticorps Siglec-1, anticorps Sn, anticorps CD169, anticorps SIGLEC-1, anticorps SN, anticorps dJ1009E24.1, anticorps SA, anticorps SIGLEC1, anticorps p210, anticorps pSn, anticorps sialic acid binding Ig like lectin 1, anticorps sialic acid binding Ig-like lectin 1, sialoadhesin, anticorps SIGLEC1, anticorps Siglec1

Sujet: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound, however, the full-length nature of this variant has not been determined.SIGLEC1 (Sialic Acid Binding Ig Like Lectin 1) is a Protein Coding gene. Diseases associated with SIGLEC1 include Proliferative Glomerulonephritis and Diffuse Cutaneous Systemic Sclerosis. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD22.

UniProt: Q9BZZ2, Q62230