CHEK2 anticorps (pThr68)
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- Antigène Voir toutes CHEK2 Anticorps
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Épitope
- pThr68
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CHEK2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Attributs du produit
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogène
- Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
- Isotype
- IgG
- Top Product
- Discover our top product CHEK2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
- Autre désignation
- CHEK2 (CHEK2 Produits)
- Synonymes
- anticorps CDS1, anticorps CHK2, anticorps HuCds1, anticorps LFS2, anticorps PP1425, anticorps RAD53, anticorps hCds1, anticorps fa66f08, anticorps wu:fa66f08, anticorps zgc:55865, anticorps Cds1, anticorps HUCDS1, anticorps Rad53, anticorps Chk2, anticorps cds1, anticorps chek2, anticorps chk2, anticorps hucds1, anticorps lfs2, anticorps pp1425, anticorps rad53, anticorps checkpoint kinase 2, anticorps serine/threonine-protein kinase chk2, anticorps checkpoint kinase 2 L homeolog, anticorps CHEK2, anticorps chek2, anticorps Chek2, anticorps MCYG_07308, anticorps chek2.L
- Sujet
- Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
- Poids moléculaire
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Observed_MW: 61 kDa
Calculated_MW: 61 kDa
- UniProt
- O96017
- Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire
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