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CHEK2 anticorps (pThr68)

CHEK2 Reactivité: Humain, Souris, Rat WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7250719
  • Antigène Voir toutes CHEK2 Anticorps
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Épitope
    • 29
    • 28
    • 21
    • 17
    • 16
    • 15
    • 15
    • 15
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr68
    Reactivité
    • 261
    • 96
    • 82
    • 16
    • 14
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 241
    • 21
    • 1
    • 1
    Lapin
    Clonalité
    • 227
    • 37
    Polyclonal
    Conjugué
    • 116
    • 14
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp CHEK2 est non-conjugé
    Application
    • 206
    • 80
    • 79
    • 71
    • 37
    • 36
    • 32
    • 28
    • 28
    • 19
    • 18
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Attributs du produit
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogène
    Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
    Isotype
    IgG
    Top Product
    Discover our top product CHEK2 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    CHEK2 (Checkpoint Kinase 2 (CHEK2))
    Autre désignation
    CHEK2 (CHEK2 Produits)
    Synonymes
    anticorps CDS1, anticorps CHK2, anticorps HuCds1, anticorps LFS2, anticorps PP1425, anticorps RAD53, anticorps hCds1, anticorps fa66f08, anticorps wu:fa66f08, anticorps zgc:55865, anticorps Cds1, anticorps HUCDS1, anticorps Rad53, anticorps Chk2, anticorps cds1, anticorps chek2, anticorps chk2, anticorps hucds1, anticorps lfs2, anticorps pp1425, anticorps rad53, anticorps checkpoint kinase 2, anticorps serine/threonine-protein kinase chk2, anticorps checkpoint kinase 2 L homeolog, anticorps CHEK2, anticorps chek2, anticorps Chek2, anticorps MCYG_07308, anticorps chek2.L
    Sujet
    Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
    Poids moléculaire

    Observed_MW: 61 kDa

    Calculated_MW: 61 kDa

    UniProt
    O96017
    Pathways
    Signalisation p53, Apoptose, Cycle Cellulaire
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