DNAJB4 anticorps

N° du produit ABIN7256592

Détail du produit anti-DNAJB4 anticorps

Antigène: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB4 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human DNAJB4 (NP_008965.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DNAJB4

Antigène: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Autre désignation: DNAJB4 (DNAJB4 Produits)

Synonymes: anticorps DNAJW, anticorps DjB4, anticorps HLJ1, anticorps 1700029A20Rik, anticorps 2010306G19Rik, anticorps 5730460G06Rik, anticorps zgc:91922, anticorps dnajb4, anticorps MGC83507, anticorps DNAJB4, anticorps DKFZp469B0618, anticorps DnaJ heat shock protein family (Hsp40) member B4, anticorps DnaJ (Hsp40) homolog, subfamily B, member 4, anticorps DnaJ heat shock protein family (Hsp40) member B4 S homeolog, anticorps DnaJ homolog subfamily B member 4, anticorps putative dnaj homolog subfamily B member 4, anticorps DNAJB4, anticorps Dnajb4, anticorps dnajb4, anticorps dnajb4.S, anticorps Bm1_16640, anticorps Smp_020920.1

Sujet: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 38 kDa

Calculated_MW: 37 kDa

ID gène: 11080

UniProt: Q9UDY4