IQGAP3 anticorps

N° du produit ABIN7257710

Détail du produit anti-IQGAP3 anticorps

Antigène: IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IQGAP3 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IQGAP3 (NP_839943.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IQGAP3

Antigène: IQGAP3 (IQ Motif Containing GTPase Activating Protein 3 (IQGAP3))

Autre désignation: IQGAP3 (IQGAP3 Produits)

Synonymes: anticorps IQGAP3, anticorps AI593484, anticorps D030034H08, anticorps IQ motif containing GTPase activating protein 3, anticorps IQGAP3, anticorps iqgap3, anticorps Iqgap3

Sujet: IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Poids moléculaire:

Observed_MW: 170 kDa

Calculated_MW: 184 kDa

ID gène: 128239

UniProt: Q86VI3