CD235b/GYPB anticorps

N° du produit ABIN7258334

Détail du produit anti-CD235b/GYPB anticorps

Antigène: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD235b/GYPB est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GYPB (NP_002091.3).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD235b/GYPB

Antigène: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Autre désignation: GYPB (GYPB Produits)

Synonymes: anticorps CD235b, anticorps GPB, anticorps GPB.NY, anticorps GYPHe.NY, anticorps GpMiIII, anticorps HGpMiIII, anticorps HGpMiVI, anticorps HGpMiX, anticorps MNS, anticorps PAS-3, anticorps SS, anticorps glycophorin B (MNS blood group), anticorps GYPB

Sujet: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97 % sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

ID gène: 2994

UniProt: P06028