FXYD1 anticorps

N° du produit ABIN7258356

Détail du produit anti-FXYD1 anticorps

Antigène: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXYD1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: A synthetic peptide of human FXYD1 (NP_005022.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FXYD1

Antigène: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Autre désignation: FXYD1 (FXYD1 Produits)

Synonymes: anticorps PLM, anticorps 0610012C17Rik, anticorps 1110006M24Rik, anticorps Plm, anticorps Pml, anticorps FXYD domain containing ion transport regulator 1, anticorps FXYD domain-containing ion transport regulator 1, anticorps FXYD1, anticorps Fxyd1

Sujet: This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.

Poids moléculaire:

Observed_MW: 16 kDa

Calculated_MW: 10 kDa

ID gène: 5348

UniProt: O00168