ATP2B2 anticorps

N° du produit ABIN7262773

Détail du produit anti-ATP2B2 anticorps

Antigène: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2B2 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ATP2B2 (NP_001674.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATP2B2

Antigène: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Autre désignation: ATP2B2 (ATP2B2 Produits)

Synonymes: anticorps PMCA2, anticorps PMCA2a, anticorps PMCA2i, anticorps ATP2B4, anticorps ATP2B2, anticorps PMCA, anticorps D6Abb2e, anticorps Tmy, anticorps dfw, anticorps jog, anticorps wms, anticorps wri, anticorps ATPase plasma membrane Ca2+ transporting 2, anticorps ATPase, Ca++ transporting, plasma membrane 2, anticorps ATP2B2, anticorps Atp2b2, anticorps atp2b2

Sujet: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire:

Observed_MW: 137 kDa

Calculated_MW: 127-136 kDa

ID gène: 491

UniProt: Q01814

Pathways: Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process