ATP6V1B1 anticorps

N° du produit ABIN7262775

Détail du produit anti-ATP6V1B1 anticorps

Antigène: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V1B1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ATP6V1B1 (NP_001683.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATP6V1B1

Antigène: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Autre désignation: ATP6V1B1 (ATP6V1B1 Produits)

Synonymes: anticorps ATP6B1, anticorps RTA1B, anticorps VATB, anticorps VMA2, anticorps VPP3, anticorps AW208839, anticorps Atp6b1, anticorps D630003L15, anticorps D630030L16Rik, anticorps D630039P21Rik, anticorps Vpp-3, anticorps Vpp3, anticorps ATPase H+ transporting V1 subunit B1, anticorps ATPase, H+ transporting, lysosomal V1 subunit B1, anticorps ATP6V1B1, anticorps Atp6v1b1

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.

Poids moléculaire:

Observed_MW: 57 kDa

Calculated_MW: 56 kDa

ID gène: 525

UniProt: P15313

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport