EXOC2 anticorps

N° du produit ABIN7264281

Détail du produit anti-EXOC2 anticorps

Antigène: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human EXOC2 (NP_060773.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EXOC2

Antigène: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Autre désignation: EXOC2 (EXOC2 Produits)

Synonymes: anticorps CG8843, anticorps Dmel\\CG8843, anticorps Sec-5, anticorps Sec5, anticorps Sec5p, anticorps dsec5, anticorps SEC5, anticorps SEC5L1, anticorps 2410030I24Rik, anticorps AI648199, anticorps Sec5l1, anticorps Rsec5, anticorps F7O12.2, anticorps F7O12_2, anticorps exocyst complex component sec5, anticorps Secretory 5, anticorps exocyst complex component 2, anticorps exocyst complex component sec5, anticorps Exocyst complex component 2, anticorps Sec5, anticorps EXOC2, anticorps Exoc2, anticorps SEC5A, anticorps sec-5

Sujet: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 108 kDa

Calculated_MW: 104 kDa

ID gène: 55770

UniProt: Q96KP1

Pathways: Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis